His-bundle pacing is the best approach to physiological pacing.

Heart Rhythm O2 · 2020 · PMC8183870 · PMID 34113860

Europe PMC DOI

hedged sentence

0.0580

closest p · 1.2× alpha

0.0580

boldest claim

The sentences

nearly reached significanceP = .058so close (0.05 < p ≤ 0.1)

Reduction in all-cause mortality nearly reached significance (hazard ratio [HR] 0.73; P = .058), and HF hospitalization was significantly reduced (HR 0.63; P = .021).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.