Interphase Chromosomes in Replicative Senescence: Chromosome Positioning as a Senescence Biomarker and the Lack of Nuclear Motor-Driven Chromosome Repositioning in Senescent Cells.

Front Cell Dev Biol · 2021 · PMC8185894 · PMID 34113611

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highly significantno p-value reported

LADs comprise about one third of the genome and so are highly significant in organising the genome within cell nuclei and have some overlap with nucleolar associated domains (NADs; Németh et al., 2010 ; van Koningsbruggen et al., 2010 ).

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