In a study to evaluate NMIBC response to BCG treatment, CyTOF was employed to observe a decreasing trend of T cell subsets in peripheral blood and corresponding tissue recruitment of immune cells in treated tumors ( 28 ), thus supporting the rationale of combining immunotherapy to overcome BCG resistance in NMIBC patients.
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Immunotherapy in the Treatment of Urothelial Bladder Cancer: Insights From Single-Cell Analysis.
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