highly significantP ≤ 3.42 x 10 -8
In fingolimod-treated patients, the decrease in BAFF-R expression was highly significant in all evaluated B cell subsets (1.77 x 10 -5 ≤ P ≤ 3.42 x 10 -8 ) and most manifest in terms of effect size on transitional B cells ( Figures 2A–D ).