Unlocking the PIP-box: A peptide library reveals interactions that drive high-affinity binding to human PCNA.

J Biol Chem · 2021 · PMC8191301 · PMID 33984330

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an interesting trendno p-value reported

The affinity of p21 μ peptides containing a native PIP-box was compared with the reported affinity of the analogous native peptide sequence to reveal an interesting trend: All five of the p21 μ native canonical PIP-box hybrid peptides display higher affinity than the native peptide ( Table 1 ).

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