Emerging Immunogenicity and Genotoxicity Considerations of Adeno-Associated Virus Vector Gene Therapy for Hemophilia.

J Clin Med · 2021 · PMC8199697 · PMID 34199563

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may be significantno p-value reported

Their work suggests there may be significant nuance in the relationship between AAV vector CpG content, innate immune signaling, and the subsequent induction of anti-capsid T-cell response.

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