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Reversible GABAergic dysfunction involved in hippocampal hyperactivity predicts early-stage Alzheimer disease in a mouse model.

Alzheimers Res Ther · 2021 · PMC8204558 · PMID 34127063

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a decreasing trendno p-value reported
In contrast to the changes in miniature events, as stimulus intensity increased, CA1 pyramidal neurons in the 5XFAD brain slices showed a decreasing trend, but with no statistical change in AMPAR EPSC amplitude (Fig. 2 F, G).

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