Gastrointestinal Bleeding and Direct Oral Anticoagulants among Patients with Atrial Fibrillation: Risk, Prevention, Management, and Quality of Life.

A recent study indicated that DAOCs have comparable QOL, greater treatment satisfaction, reduced hospitalization, and a nonsignificant trend toward fewer bleeding episodes when compared with warfarin. 89 Major GIB events in DOAC users are generally associated with favorable outcomes which is an important aspect that can influence HRQOL. 90 In a European survey discontinuation related to bleeding was evident in only 4% of the patient

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