Translation reprogramming by eIF3 linked to glioblastoma resistance.

This result was reinforced by data extracted from the Oncomine database ( http://www.oncomine.org ), where several sets that compare expression in GBM with normal brain show a highly significant increase in eIF3e mRNA levels ( Supplementary Figure S5A ).

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We observed an overall trend of increased eIF3e expression in recurrent tumors compared with primary untreated tumor sections (Figure 5D ).

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