Major Differences in Lymphocyte Subpopulations Between Cerebrospinal Fluid and Peripheral Blood in Non-Hodgkin Lymphoma Without Leptomeningeal Involvement: Flow Cytometry Evidence of a Cerebral Lymphatic System.

The highly significant differences between CSF and paired peripheral blood lymphoid phenotype ( p <0.0001) confirms the existence of an active mechanism of lymphoid migration through the meninges. cerebrospinal fluid lymphocytes flow cytometry NHL cerebral lymphatic system The CSF population was represented by lymphocytes (77%; range 20–100%) together with a minor population of monocytes (CD4-weak or CD14-positive 15%; range 0–70%).

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