Cut-off values of lesion and vessel quantitative flow ratio in de novo coronary lesion post-drug-coated balloon therapy predicting vessel restenosis at mid-term follow-up.

[ 19 – 21 ] Several studies have even indicated that DCB-treated de novo lesions had favorable vessel remodeling without chronic elastic recoil during follow-up [ 22 , 23 ] and that the majority of plaque composition is fibrous, with an increasing trend in the fibrofatty tissue from baseline to 9 months follow-up.

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