Runx1 shapes the chromatin landscape via a cascade of direct and indirect targets.

PLoS Genet · 2021 · PMC8219162 · PMID 34111109

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highly significantno p-value reported

Regulatory Element Locus Intersection (RELI) analyses [ 32 ] confirmed the highly significant agreement between the Runx1 (mk4), Runx2 (mk4), and Runx2 (Runx1 KO) ChIP-seq datasets (control cell 194.46 fold enriched, p-value 2.0 x 10 −219 ; Runx1KO cell 177.85 fold enriched, p-value 2.32 x 10 −219 ; S2C Fig and S4 Table ).

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