Impact of antibiotic usage on extended-spectrum β-lactamase producing Escherichia coli prevalence.

Sci Rep · 2021 · PMC8219833 · PMID 34158540

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an increasing trendno p-value reported

Similarly, antimicrobial use density (AUD) of ciprofloxacin β = 1383.6622 , P = 0.0026 , cefepime β = 961.8701 , P < 0.0001 , piperacillin-tazobactam β = 2457.3924 , P < 0.0001 , and third-generation cephalosporine ( β = 3035.1029, P < 0.0001 ) consumption showed an increasing trend over time (Fig. 2 ).

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