<i>NOTCH3</i> variants are more common than expected in the general population and associated with stroke and vascular dementia: an analysis of 200 000 participants.

J Neurol Neurosurg Psychiatry · 2021 · PMC8223663 · PMID 33712516

Europe PMC DOI

hedged sentences

0.0480

closest p · 1.0× alpha

0.0480

boldest claim

The sentences

borderline significantp=0.048actually significant

There was a borderline significant increase in epilepsy (OR:1.92, 95% CI: 1.01 to 3.29, p=0.048).

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marginally significantno p-value reported

We also found trends towards other clinical features of CADASIL being more common with these variants with a marginally significant association with epilepsy, and a non-significant trend towards increased risk of migraine.

also in 26,082 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.

&lt;i&gt;NOTCH3&lt;/i&gt; variants are more common than expected in the general population and associated with stroke and vascular dementia: an analysis of 200 000 participants.

The sentences

<i>NOTCH3</i> variants are more common than expected in the general population and associated with stroke and vascular dementia: an analysis of 200 000 participants.