highly significantP = 1.5 × 10 −4
Alternatively, we simply counted the number of genes that had a higher coefficient of variation for the UM state compared to the gbM state; 5357 (or 61.56%) genes had more variable expression among UM epialleles, representing a highly significant deviation from the null expectation of 50% (binomial test, two-sided, P = 1.5 × 10 −4 ).