Efficacy and safety of tadalafil in a pediatric population with pulmonary arterial hypertension: phase 3 randomized, double-blind placebo-controlled study.

Pulm Circ · 2021 · PMC8226239 · PMID 34234945

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a positive trendno p-value reported

There was also a positive trend of potential efficacy in the majority of the measurements from this study, such as NT-Pro-BNP, WHO functional class for Period 1, echocardiographic parameters (such as TAPSE, left ventricular EI-systolic, left ventricular EI-diastolic), and CGI-I.

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