Genomic imbalance determines positive and negative modulation of gene expression in diploid maize.

Concluding remarks In general, the results of this study illustrate that there is an overall trend for greater gene expression modulation in aneuploids than in a ploidy series, which provides insight into the century-old observation that changing the dosage of individual chromosomes has more phenotypic effects than changing the whole set.

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K–S tests for different distributions and Bartlett’s tests for variations both showed highly significant differences ( Supplemental Data Sets 3 and 4 ), suggesting a greater level of disruption of global gene expression in aneuploidy than in ploidy.

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