Comparative Study of SARS-CoV-2, SARS-CoV-1, MERS-CoV, HCoV-229E and Influenza Host Gene Expression in Asthma: Importance of Sex, Disease Severity, and Epithelial Heterogeneity.

Viruses · 2021 · PMC8226441 · PMID 34198852

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marginally significantno p-value reported

For SARS-CoV-2 related genes, we found marginally significant downregulation of viral entry receptor ACE2 in females in Th2 high asthma and significant downregulation in males in mild asthma in the upper airway (6.9% decrease) ( Figure 1 a).

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