Neuroprotective Effects of Tripeptides-Epigenetic Regulators in Mouse Model of Alzheimer's Disease.

Pharmaceuticals (Basel) · 2021 · PMC8227791 · PMID 34071923

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a pronounced trendno p-value reported

In addition, a pronounced trend of LTP increase in the 5xFAD mice with the KED peptide effect suggested that this peptide may be able to restore neuroplasticity at the early stages of AD.

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a positive trendno p-value reported

There was also a positive trend for the EDR and KED peptides to restore LTP in 5xFAD mice, although it has not reached the statistical significance level.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.