extremely significantp < 0.001
Statistical analysis showed that the difference between the size of the capsule formed by the vlp1 Δ mutant or the VLP1 overexpression strains and that of the capsule formed by the wild-type strain was extremely significant ( Figure 2 C, p < 0.001 and p < 0.0001, respectively, Student’s t -test), indicating that the Vlp1 proteins played an important role in the formation of the cryptococcal capsules.