highly significantp = 0.002
A forest plot ( Figure 3 a) from three studies (MED range; 1.0–2.5) of oral intake studies with healthy participants ( n = 175) revealed a highly significant pooling difference ( p = 0.002) in pre-and post-intervention changes in erythema index (SMD: −0.35; 95% CI, −0.57 to −0.13; I 2 = 4%, p = 0.40) in the random-effects model.