Although the vast majority of DGR gene targets were not functionally annotated, we observed highly significant enrichment within several Pfam domains (Supplementary Table 7 ) including an immunoglobulin-like domain that was 5.9-fold more common among DGR-targeted genes and is believed to play a role in phage interactions with carbohydrates on the cell surface of bacteria 70 .
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Metagenomic compendium of 189,680 DNA viruses from the human gut microbiome.
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