Non-canonical function of DGCR8 in DNA double-strand break repair signaling and tumor radioresistance.

Nat Commun · 2021 · PMC8242032 · PMID 34188037

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highly significantP < 1 × 10 −15actually significant

We also plotted the USP51 protein score versus the DGCR8 protein score for individual patients, which revealed a highly significant correlation (Pearson R 2 = 0.52, P < 1 × 10 −15 ; Supplementary Fig. 7c ), indicating the relevance of the identified regulatory mechanism in human cancer.

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