Barely Significant
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Opioids and the Risk of Fracture: A Self-Controlled Case Series Study in the Clinical Practice Research Datalink.

Am J Epidemiol · 2021 · PMC8245882 · PMID 33604606

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a weak trendno p-value reported
Opioid use was significantly associated with an increased risk of falls, which was greatest in the first week of opioid exposure; however, only a weak trend was observed when restricted to falls without fracture (Web Figure 7).

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