A hyaluronic acid-based filler reduces lipolysis in human mature adipocytes and maintains adherence and lipid accumulation of long-term differentiated human preadipocytes.

In addition, we found that adding of cross‐linked HA in the culture media of the encapsulated adipocytes remarkably reduced the basal and the isoproterenol‐induced lipolysis (stimulated lipolysis) that were highly significant with cross‐linked HA 0.3% in both conditions (Figure 4C,D ). 4.

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