Comparison of the two doses showed a numerical trend towards higher responses with 2 mg kg −1 vs. 4 mg kg −1 in the treatment of AD signs and symptoms in both the phase IIa and OLE studies.
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Dupilumab provides favourable long-term safety and efficacy in children aged ≥ 6 to < 12 years with uncontrolled severe atopic dermatitis: results from an open-label phase IIa study and subsequent phase III open-label extension study.
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