Barely Significant
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Increased extracellular fluid is associated with white matter fiber degeneration in CADASIL: in vivo evidence from diffusion magnetic resonance imaging.

Fluids Barriers CNS · 2021 · PMC8247253 · PMID 34193191

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marginally significantno p-value reported
Second, disease duration had a negative correlation (marginally significant) with AFD but not with FW in FWq3 and FWq4, suggesting that fiber disruption occurred at relatively late disease stages.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.