borderline significantp = 0.045
However, for CD, the numerical trend toward lower estimates with increasing cumulative DDD category was more pronounced, with the highest category [>1500 DDD] yielding a multivariable OR of 0.57 [95% CI, 0.41–0.79]. We additionally ran analyses for cumulative statin dose excluding the small number of statin users where total DDD was truncated [ Supplementary Table 3, available as Supplementary data at ECCO-JCC online ]. The results were similar to those of our main analysis although, for CD, the test of linear trend was borderline significant [ p = 0.045]. 3.3.