They reported that PLGA particles modified by pulmonary endogenous phospholipids (DPPS, DPPG, and DSPE) showed an obvious trend of binding with pulmonary macrophages, while pegylated DSPE (PEG2000-DSPE) modified PLGA particles showed obvious poor binding with pulmonary macrophages.
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PLGA-based biodegradable microspheres in drug delivery: recent advances in research and application.
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