Genetic variant in 3' untranslated region of the mouse <i>pycard</i> gene regulates inflammasome activity.

Elife · 2021 · PMC8248980 · PMID 34197316

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highly significantno p-value reported

A highly significant QTL mapped to distal chromosome 7 (log10 of the odds score (LOD) = 8.60, peak position = 134.80 Mb), which we named inflammatory response modulator 3 ( Irm3 ) in accordance with Mouse Genome Informatics nomenclature conventions ( Figure 1B ).

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