Functional connectivity of the human hypothalamus during wakefulness and nonrapid eye movement sleep.

Hum Brain Mapp · 2021 · PMC8249893 · PMID 33960583

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an increasing trendno p-value reported

Additionally, the insular cortex and frontal operculum cortex showed negative connectivity during wakefulness and positive connectivity during sleep with the anterior hypothalamus, exhibiting an increasing trend.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.