Comparison of the injection-site experience of the starting doses with semaglutide and dulaglutide: A randomized, double-blind trial in healthy subjects.

A decreasing trend in mean reported pain level from 1.2 to 0.8 (on a 0–10 integer scale) over the course of four injections was observed in patients who injected themselves once weekly with a placebo‐filled dulaglutide pen‐injector. 6 However, it is plausible that a similar decrement would apply to semaglutide.

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