Enantioselective Synthesis of α-Aryl-β<sup>2</sup> -Amino-Esters by Cooperative Isothiourea and Brønsted Acid Catalysis.

Angew Chem Int Ed Engl · 2021 · PMC8252622 · PMID 33646631

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highly significantno p-value reported

The nature of the base present in the reaction is therefore highly significant, presumably effecting both iminium ion and C(1)‐ammonium enolate formation though modulation of equilibrium distributions.

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