Regulation of the mammalian maternal-to-embryonic transition by eukaryotic translation initiation factor 4E.

Analysis of the distribution of embryos between each of the expected genotypes showed that, at the four- to eight-cell stage, fewer Eif4e −/− embryos were detected than expected ( P <0.02) ( Table 3 ), whereas, at the blastocyst stage, this skew did not achieve significance for the sample size available ( P >0.05).

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