Pharmacogenomics of NSAID-Induced Upper Gastrointestinal Toxicity.

Front Pharmacol · 2021 · PMC8256335 · PMID 34234675

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highly significantno p-value reported

Furthermore, allele-specific analyses showed that CYP2C9*2 was a poor risk predictor (marginal effects) in contrast to CYP2C9*3 , which clearly showed a highly significant association with increased risk of upper GI adverse events and GI bleeding ( Macías et al., 2020 ).

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