Alcohol Consumption and Risk of Common Autoimmune Inflammatory Diseases-Evidence From a Large-Scale Genetic Analysis Totaling 1 Million Individuals.

Front Genet · 2021 · PMC8258244 · PMID 34239545

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marginal significanceP = 0.06so close (0.05 < p ≤ 0.1)

Inflammatory bowel disease, RA, and MS are Th1-related autoimmune disorders, meta-analyzing across these three traits yielded to a reduced effect with marginal significance [OR meta (95%CI) = 0.79 (0.63–1.01), P = 0.06 using all IVs; OR meta (95%CI) = 0.70 (0.51–0.95), P = 0.02 using IVs excluding confounders].

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