Divergent trends of hospitalizations for upper and lower gastrointestinal bleeding based on population prescriptions of aspirin, proton pump inhibitors and Helicobacter pylori eradication therapy: Trends of upper and lower gastrointestinal bleeding.

United European Gastroenterol J · 2021 · PMC8259432 · PMID 33956403

Europe PMC DOI

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an increasing trendno p-value reported

2 found an increasing trend of lower GI complications, particularly in patients >60 years.

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a decreasing trendno p-value reported

30 also reported a decreasing trend in patients <70 years.

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a nonsignificant trendno p-value reported

pylori eradication in the previous month showed a nonsignificant trend on UGIB (coefficient −0.14; 95% CI: −0.30, 0.02).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.