Barely Significant
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Full assembly of HIV-1 particles requires assistance of the membrane curvature factor IRSp53.

Elife · 2021 · PMC8260224 · PMID 34114563

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The sentences

highly significantp value = 0.00265actually significant
This reduction in HIV-1 particle release is highly significant ( n = 3 independent experiments, p value = 0.00265, Student’s t -test, and ANOVA statistical test for multiple comparisons indicate p value = 0.0089) since the gene editing of IRSp53 cannot be complete, nor edited by CRISPR/Cas9 knockout, without being toxic for the cells.

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