HSD17B7 gene in self-renewal and oncogenicity of keratinocytes from Black versus White populations.

Clustering of the signature genes by the Manhattan distance metrics method (Shirkhorshidi et al , 2015 ) identified four main groups of co‐expressed genes (Fig 3A ), with gene ontology (GO) analysis showing highly significant enrichment of gene families involved in various metabolic and detoxification processes, with similar or identical functional categories when HKCs from Black individuals were considered as a total group or one with < 20% genomic admixture (Fig 3B and Dataset EV1 ).

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