Several studies were able to demonstrate that an increasing trend of SARS-CoV-2 in wastewater preceded a rise in clinical cases by up to one week ( Peccia et al., 2020 ; Randazzo et al., 2020 ; Wurtzer et al., 2020 ), establishing the potential utility of COVID-19 WBE as an “early warning system” to mitigate viral spread and cost effective strategy for monitoring real-time changes in viral prevalence.
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A direct capture method for purification and detection of viral nucleic acid enables epidemiological surveillance of SARS-CoV-2.
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