An interim analysis performed after accrual of 60 patients with 46 evaluable (median follow-up = 13 months) showed a greater than expected, statistically highly significant difference in PFS between the iFLT-PET/CT-positive and iFDG-PET/CT-positive patients (47% difference, 9% PFS for iFLT vs. 56% PFS for iFDG) with negligible difference in NPV between iFDG-PET/CT and iFLT-PET/CT (1% difference, 94% for iFLT vs. 95% for iFDG).
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<sup>18</sup>F-Fluorothymidine PET is an early and superior predictor of progression-free survival following chemoimmunotherapy of diffuse large B cell lymphoma: a multicenter study.
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