Differences in treatment effect size between progression-free survival and overall survival in anti-PD-1/PD-L1 inhibitors-based trials in advanced NSCLC: a systematic review and meta-analysis.

Transl Lung Cancer Res · 2021 · PMC8264319 · PMID 34295662

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highly significantno p-value reported

Moreover, a highly significant correlation between HRs of PFS and OS was observed in monotherapy group and first-line setting group, suggesting a high feasibility of utilizing PFS as surrogate for OS in this clinical scenario.

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