a trend towards significanceP = 0.09
Although age, sex, ulceration, stage, LN metastasis, and remote metastasis did not show statistically significant correlations with TFPI2, there seemed to be a trend towards significance between the positive staining of TFPI2 with advanced stages ( P = 0.09) and lymph node metastasis ( P = 0.07) in the TMU-CM cohort ( Supplementary Table 8 ).