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The Effect of Intravenous Autologous Activated Platelet-Rich Plasma Therapy on "Profibrotic Cytokine" IL-1<i>β</i> Levels in Severe and Critical COVID-19 Patients: A Preliminary Study.

Scientifica (Cairo) · 2021 · PMC8266471 · PMID 34306796

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a decreasing trendno p-value reported
Patients who recovered had a decreasing trend in plasma IL-1 β concentration by day 6 of the study, while patients who died had their plasma IL-1 β concentration increased by day 4 and 6 Figure 2 .

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.