Differential Cytokine Responses in Hospitalized COVID-19 Patients Limit Efficacy of Remdesivir.

Despite an indication of increasing T h 2 responses in responders, a decreasing trend approaching healthy baseline was observed for pro-inflammatory IL-6 levels one-week post-treatment ( Figure 3C ).

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For T h 2-associated cytokine IL-21, although treatment did not significantly impact IL-21 levels in both treated and control patients, there was an increasing trend for IL-21 in responders ( Figure 3B ).

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