Adipose mesenchymal stem cells combined with platelet-rich plasma accelerate diabetic wound healing by modulating the Notch pathway.

Stem Cell Res Ther · 2021 · PMC8276220 · PMID 34256844

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These results were accompanied by a highly significant increase in gene expression of Notch-1 signaling pathway, as there was pathological over-activation of notch1 and its downstream genes, combined with a significant decrease in gene expression of VEGF, SDF-1, and EPSCm (ß Integrin).

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