Alterations in Gene Expression of Renin-Angiotensin System Components and Related Proteins in Colorectal Cancer.

Angiotensinogen ( AGT ) There was a large highly significant increase of 2.413 log units in AGT gene expression suggesting increased production of the angiotensinogen precursor of the angiotensin peptides in colorectal tumor tissue ( Table 1 ). 3.1.2.

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There was a marginally significant reduction in gene expression for PRCP , ACE2 , and AGT in stage 2B relative to stage 1, but this did not approach statistical significance for a multiple comparison correction.

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