borderline significanceP=0.063
Further, correlation analysis between KL methylation profile and clinicopathol ogical features of our cohort using Fisher-Freeman-Halton Exact test revealed significant associations between KL methylation pattern and tumor subtype (P<0.0001), tumor site (P=0.036), and borderline significance for endpoint status (P=0.063), and age (P=0.064) ( Table I ).