Beyond the 'purple drank': Study of promethazine abuse according to the European Medicines Agency adverse drug reaction reports.

Vulnerable categories An increasing trend in abuse of promethazine in co-formulation with some components of OTC cough medications has been reported in young adult populations ( Carney et al., 2018 ; Carr, 2006 ; Höjer and Tellerup, 2018 ) since the late 1990s, particularly in the southern USA ( Carr, 2006 ; Elwood, 2001 ).

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