Myeloid Endoplasmic Reticulum Resident Chaperone GP96 Facilitates Inflammation and Steatosis in Alcohol-Associated Liver Disease.

Alcohol‐induced CHOP protein show a decreasing trend in alcohol‐fed M‐GP96KO mice livers (Fig. 6D ), whereas protein levels of cleaved ATF6α and nuclear ATF4 were not significantly changed.

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The mRNA and protein levels of GP96 showed an increasing trend in alcohol‐fed WT littermates (Fig. 1C ), whereas the mRNA induction in livers of alcohol‐fed C57BL/6J compared with pair‐fed controls reached significance (Supporting Fig.

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